Symposium C3. Biointerface and Biosensor with Nanostructure and Biopolymers

Ting-Yu LiuMing Chi University of Technology
Shyh-Chyang LuoNational Taiwan University
Aya Mizutani AkimotoUniversity of Tokyo
Scope & Topics

Nanobiotechnology is a rapidly growing field to fabricate smart biointerfaces and ultra-sensitive biosensors. Nanostructures are commonly used for biointerfaces and biosensors, including soft biomaterials (hydrogels and biopolymers), metallic nanomaterials (gold and silver nanoparticles), and semiconductor materials (silicon nanowires, carbon nanomaterials, and nanoporous materials). For example, the functionalized surfaces of gold or biodegradable nanoparticles are often used in drug delivery for cancer therapy. The nanoarrays of gold/silver nanoparticles can also be applied in surface enhanced Raman scattering (SERS) detection and electrochemical biosensors. Besides, for the application soft biomaterials, such hydrogels and biopolymers, to manipulate cell fate for realization of the regenerative medicine. An important thing is to control the interaction is to quantitatively understand their biointerface. Furthermore, the activity of biomolecules and cell behavior on the surfaces can also be manipulated through the modulation of stimuli-responsive biomaterials, including pH, thermal, and electrical stimuli. In this symposium, the topic will be focused on the issues of advanced nanobiotechnology and biosensors to discuss the interaction between biointerface and cells/microorganisms, as well as the sensitivity and reproducibility of the biosensors.